Benet Pera : rechercher sur Z-Library

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1

Mechanism of Action of the Cytotoxic Macrolides Amphidinolide X and J

Chiara Trigili, Benet Pera, Dr. Marion Barbazanges, Prof. Dr. Janine Cossy, Dr. Christophe Meyer, Dr. Oriol Pineda, Dr. Carles Rodríguez-Escrich, Prof. Fèlix Urpí, Prof. Dr. Jaume Vilarrasa, Dr. J. F

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 615 KB

english, 2011

2

Cyclostreptin Derivatives Specifically Target Cellular Tubulin and Further Map the Paclitaxel Site

Calvo, Enrique, Barasoain, Isabel, Matesanz, Ruth, Pera, Benet, Camafeita, Emilio, Pineda, Oriol, Hamel, Ernest, Vanderwal, Christopher D., Andreu, José Manuel, López, Juan A.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 3.80 MB

english, 2012

3

THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors

Cayrol, Florencia, Praditsuktavorn, Pannee, Fernando, Tharu M., Kwiatkowski, Nicholas, Marullo, Rosella, Calvo-Vidal, M. Nieves, Phillip, Jude, Pera, Benet, Yang, Shao Ning, Takpradit, Kaipol, Roman,

Journal:

Nature Communications

Année:

2017

Langue:

english

Fichier:

PDF, 2.35 MB

english, 2017

4

Molecular Recognition of Peloruside A by Microtubules. The C24 Primary Alcohol is Essential for Biological Activity

Benet Pera, Mina Razzak, Chiara Trigili, Oriol Pineda, Angeles Canales, Rubén M. Buey , Jesús Jiménez-Barbero, Peter T. Northcote, Ian Paterson, Isabel Barasoain, José Fernando Díaz

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 863 KB

english, 2010

5

Corrigendum: Mechanism of Action of the Cytotoxic Macrolides Amphidinolide X and J

Chiara Trigili, Benet Pera, Dr. Marion Barbazanges, Prof. Dr. Janine Cossy, Dr. Christophe Meyer, Dr. Oriol Pineda, Dr. Carles Rodríguez-Escrich, Prof. Fèlix Urpí, Prof. Dr. Jaume Vilarrasa, Dr. J. F

Journal:

Année:

2011

Fichier:

PDF, 55 KB

2011

6

The Binding Mode of Side Chain- and C3-Modified Epothilones to Tubulin

Máté Erdélyi, Armando Navarro-Vázquez, Bernhard Pfeiffer, Christian N. Kuzniewski, Andrea Felser, Toni Widmer, Jürg Gertsch, Benet Pera, José Fernando Díaz, Karl-Heinz Altmann, Teresa Carlomagno

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 646 KB

english, 2010

7

Corrigendum: Mechanism of Action of the Cytotoxic Macrolides Amphidinolide X and J

Chiara Trigili, Benet Pera, Dr. Marion Barbazanges, Prof. Dr. Janine Cossy, Dr. Christophe Meyer, Dr. Oriol Pineda, Dr. Carles Rodríguez-Escrich, Prof. Fèlix Urpí, Prof. Dr. Jaume Vilarrasa, Dr. J. F

Journal:

Année:

2012

Fichier:

PDF, 93 KB

2012

8

Zampanolide, a Potent New Microtubule-Stabilizing Agent, Covalently Reacts with the Taxane Luminal Site in Tubulin α,β-Heterodimers and Microtubules

Jessica J. Field, Benet Pera, Enrique Calvo, Angeles Canales, Didier Zurwerra, Chiara Trigili, Javier Rodríguez-Salarichs, Ruth Matesanz, Arun Kanakkanthara, St. John Wakefield, A. Jonathan Singh, Jes

Journal:

Chemistry & Biology

Année:

2012

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2012

9

Structure–activity relationships of novel substituted naphthalene diimides as anticancer agents

Milelli, Andrea, Tumiatti, Vincenzo, Micco, Marialuisa, Rosini, Michela, Zuccari, Guendalina, Raffaghello, Lizzia, Bianchi, Giovanna, Pistoia, Vito, Fernando Díaz, J., Pera, Benet, Trigili, Chiara, Ba

Journal:

European Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2012

10

Modulation of Microtubule Interprotofilament Interactions by Modified Taxanes

Matesanz, Ruth, Rodríguez-Salarichs, Javier, Pera, Benet, Canales, Ángeles, Andreu, José Manuel, Jiménez-Barbero, Jesús, Bras, Wim, Nogales, Aurora, Fang, Wei-Shuo, Díaz, José Fernando

Journal:

Biophysical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2011

11

A structure-based design of new C2- and C13-substituted taxanes: tubulin binding affinities and extended quantitative structure–activity relationships using comparative binding energy (COMBINE) analysis

Coderch, Claire, Tang, Yong, Klett, Javier, Zhang, Shu-En, Ma, Yun-Tao, Shaorong, Wang, Matesanz, Ruth, Pera, Benet, Canales, Angeles, Jiménez-Barbero, Jesús, Morreale, Antonio, Díaz, J. Fernando, Fan

Journal:

Organic & Biomolecular Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 2.84 MB

english, 2013

12

PM060184, a new tubulin binding agent with potent antitumor activity including P-glycoprotein over-expressing tumors

Martínez-Díez, Marta, Guillén-Navarro, María José, Pera, Benet, Bouchet, Benjamin Pierre, Martínez-Leal, Juan Fernando, Barasoain, Isabel, Cuevas, Carmen, Andreu, Jose M., García-Fernández, Luis Franc

Journal:

Biochemical Pharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 2.92 MB

english, 2014

13

New Interfacial Microtubule Inhibitors of Marine Origin, PM050489/PM060184, with Potent Antitumor Activity and a Distinct Mechanism

Pera, Benet, Barasoain, Isabel, Pantazopoulou, Areti, Canales, Angeles, Matesanz, Ruth, Rodriguez-Salarichs, Javier, García-Fernandez, Luis F., Moneo, Victoria, Jiménez-Barbero, Jesús, Galmarini, Carl

Journal:

ACS Chemical Biology

Année:

2013

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2013

14

Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances

Matesanz, Ruth, Trigili, Chiara, Rodríguez-Salarichs, Javier, Zanardi, Ilaria, Pera, Benet, Nogales, Aurora, Fang, Wei-Shuo, Jímenez-Barbero, Jesús, Canales, Ángeles, Barasoain, Isabel, Ojima, Iwao, D

Journal:

Bioorganic & Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 2.59 MB

english, 2014

15

Epigenetic Cancer Therapy || Personalized Epigenetic Therapy—Chemosensitivity Testing

Année:

2015

Langue:

english

Fichier:

PDF, 307 KB

english, 2015

16

High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cells

Pera, Benet, Calvo-Vidal, M. Nieves, Ambati, Srikanth, Jordi, Michel, Kahn, Alissa, Díaz, J. Fernando, Fang, Weishuo, Altmann, Karl-Heinz, Cerchietti, Leandro, Moore, Malcolm A.S.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2015

17

Combinatorial epigenetic therapy in diffuse large B cell lymphoma pre-clinical models and patients

Pera, Benet, Tang, Tiffany, Marullo, Rossella, Yang, Shao-Ning, Ahn, Haelee, Patel, Jayeshkumar, Elstrom, Rebecca, Ruan, Jia, Furman, Richard, Leonard, John, Cerchietti, Leandro, Martin, Peter

Journal:

Clinical Epigenetics

Année:

2016

Langue:

english

Fichier:

PDF, 2.74 MB

english, 2016

18

Corrigendum: THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors

Cayrol, Florencia, Praditsuktavorn, Pannee, Fernando, Tharu M., Kwiatkowski, Nicholas, Marullo, Rossella, Calvo-Vidal, M. Nieves, Phillip, Jude, Pera, Benet, Yang, Shao Ning, Takpradit, Kaipol, Roman,

Journal:

Nature Communications

Année:

2017

Langue:

english

Fichier:

PDF, 130 KB

english, 2017

19

Zampanolide Binding to Tubulin Indicates Cross-Talk of Taxane Site with Colchicine and Nucleotide Sites

Field, Jessica J., Pera, Benet, Gallego, Juan Estévez, Calvo, Enrique, Rodríguez-Salarichs, Javier, Sáez-Calvo, Gonzalo, Zuwerra, Didier, Jordi, Michel, Andreu, José M., Prota, Andrea E., Ménchon, Gré

Journal:

Journal of Natural Products

Année:

2017

Langue:

english

Fichier:

PDF, 6.81 MB

english, 2017

20

Metabolomic Profiling Reveals Cellular Reprogramming of B-Cell Lymphoma by a Lysine Deacetylase Inhibitor through the Choline Pathway

Pera, Benet, Krumsiek, Jan, Assouline, Sarit E., Marullo, Rossella, Patel, Jayeshkumar, Phillip, Jude M., Román, Lidia, Mann, Koren K., Cerchietti, Leandro

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 2.24 MB

english, 2018

21

BCL6 evolved to enable stress tolerance in vertebrates and is broadly required by cancer cells to adapt to stress

Fernando, Tharu M, Marullo, Rossella, Pera Gresely, Benet, Phillip, Jude M., Yang, Shao Ning, Lundell-Smith, Geoffrey, Torregroza, Ingrid, Ahn, Haelee, Evans, Todd, Gyorffy, Balazs, Prive, Gilbert G,

Journal:

Cancer Discovery

Année:

2019

Langue:

english

Fichier:

PDF, 2.16 MB

english, 2019